Premature ovarian failure (POF), also known as primary ovarian insufficiency, is a condition characterized by loss of normal function of the ovaries before age 40. The causes of POF are often unknown, but can include genetics, autoimmune disorders, infections, chemotherapy treatment, and more.
Some key facts about premature ovarian failure:
- It affects roughly 1% of women under age 40, and 0.1% under age 30
- The main symptom is irregular periods or missed periods, but some women still ovulate occasionally
- Women with POF typically have hot flashes and other menopausal symptoms
- There is an increased risk of osteoporosis and heart disease
- Most women with POF will need to take hormone replacement with estrogen and progesterone to protect their health
Diagnosis involves blood tests to measure hormone levels like FSH and estradiol. Pelvic ultrasound may also be used to examine the ovaries.
Some treatment options for
POF include:
- Hormone replacement therapy: Usually a combination estrogen/progesterone pill or patch to replace missing hormones
- Osteoporosis prevention with calcium, vitamin D, and possibly bisphosphonates
- Donor egg IVF if trying to achieve pregnancy
- Emotional support to cope with the diagnosis
If you've been diagnosed with premature ovarian failure, the specialists at
Hormone Harmony Clinic can help. Our compassionate team includes reproductive endocrinologists and clinicians experienced in supporting women with
POF. We provide customized
hormone replacement regimens using cutting-edge bioidentical hormones to help relieve your symptoms. And if you want to get pregnant, we offer advanced fertility treatments like
donor eggs and gestational surrogacy. Contact us today for a consultation!